Entity Details

Primary name RTEL1
Entity type gene
Source Source Link

Details

PrimaryID51750
RefseqGeneNG_033901
SymbolRTEL1
Nameregulator of telomere elongation helicase 1
Chromosome20
Location20q13.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-21
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsRTEL1_HUMAN

GO terms

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GOName
GO:0000723 telomere maintenance
GO:0000732 strand displacement
GO:0000781 chromosome, telomeric region
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006281 DNA repair
GO:0007004 telomere maintenance via telomerase
GO:0010569 regulation of double-strand break repair via homologous recombination
GO:0031297 replication fork processing
GO:0032206 positive regulation of telomere maintenance
GO:0032508 DNA duplex unwinding
GO:0043247 telomere maintenance in response to DNA damage
GO:0045910 negative regulation of DNA recombination
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0070182 DNA polymerase binding
GO:0090657 telomeric loop disassembly
GO:1902990 mitotic telomere maintenance via semi-conservative replication
GO:1904355 positive regulation of telomere capping
GO:1904358 positive regulation of telomere maintenance via telomere lengthening
GO:1904430 negative regulation of t-circle formation
GO:1904506 negative regulation of telomere maintenance in response to DNA damage
GO:1904535 positive regulation of telomeric loop disassembly

Diseases

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Interactions

52 interactions

InteractorPartnerSourcesPublicationsLink
RTEL1SLX4BioGRID31495888 32398829 details
RTEL1MMS19BioGRID, IntAct22678361 22678362 23585563 28178521 details
RTEL1TOP3BBioGRID29395067 details
RTEL1ERCC4BioGRID32398829 details
RTEL1POLR2ABioGRID32398829 details
RTEL1CUL3BioGRID, IntAct21145461 details
RTEL1XRCC5BioGRID, IntAct26496610 details
RTEL1LIMK1BioGRID, IntAct26496610 details
RTEL1NCK1BioGRID, IntAct26496610 details
RTEL1INTS14BioGRID, IntAct26496610 details
RTEL1KATNA1BioGRID, IntAct26496610 details
RTEL1SASS6BioGRID, IntAct26496610 details
RTEL1CIAO2BBioGRID, IntAct23891004 28178521 details
RTEL1PDCD1BioGRID, IntAct28514442 details
RTEL1NEUROG3BioGRID, IntAct28514442 details
RTEL1VWA5ABioGRID, IntAct28514442 details
RTEL1EFNB3BioGRID, IntAct28514442 details
RTEL1ZNRD2BioGRID, IntAct28514442 details
RTEL1CBWD1BioGRID, IntAct26186194 28514442 details
RTEL1ISLRBioGRID, IntAct26186194 28514442 details
RTEL1PSME3BioGRID, IntAct26186194 28514442 details
RTEL1NCAPH2BioGRID, IntAct28514442 details
RTEL1SKAP1BioGRID, IntAct26186194 28514442 details
RTEL1SLC18A1BioGRID, IntAct28514442 details
RTEL1GATD1BioGRID, IntAct28514442 details
RTEL1LRP1BioGRID, IntAct28514442 details
RTEL1TUBBBioGRID, IntAct28514442 details
RTEL1PPM1ABioGRID, IntAct26186194 28514442 details
RTEL1ARL15BioGRID, IntAct28514442 details
RTEL1LIPHBioGRID, IntAct26186194 28514442 details
RTEL1UBXN11BioGRID, IntAct26186194 28514442 details
RTEL1RPA1BioGRID24332808 details
RTEL1RPA2BioGRID24332808 details
RTEL1RPA3BioGRID24332808 details
RTEL1CIAO1BioGRID23891004 details
RTEL1THBS3BioGRID26186194 details
RTEL1RAD51BioGRID26496610 details
RTEL1VAV2BioGRID26496610 details
RTEL1FAM13ABioGRID26496610 details
RTEL1GAS2L1BioGRID26496610 details
RTEL1PRSS21BioGRID26496610 details
RTEL1WDFY3BioGRID26496610 details
RTEL1ANKLE2BioGRID26496610 details
RTEL1ATP13A2BioGRID26496610 details
RTEL1AATFBioGRID26496610 details
RTEL1NDUFA13BioGRID26496610 details
RTEL1SS18L2BioGRID26496610 details
RTEL1EMSYBioGRID26496610 details
RTEL1THAP11BioGRID26496610 details
RTEL1CCNYL1BioGRID26496610 details
RTEL1DCAF15BioGRID31452512 details
RTEL1HNRNPLBioGRID28611215 details