Entity Details

Primary name AXL
Entity type gene
Source Source Link

Details

PrimaryID558
RefseqGene
SymbolAXL
NameAXL receptor tyrosine kinase
Chromosome19
Location19q13.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-07-06
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsUFO_HUMAN

GO terms

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GOName
GO:0001618 virus receptor activity
GO:0001764 neuron migration
GO:0001779 natural killer cell differentiation
GO:0001786 phosphatidylserine binding
GO:0001961 positive regulation of cytokine-mediated signaling pathway
GO:0001974 blood vessel remodeling
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006909 phagocytosis
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0007399 nervous system development
GO:0009986 cell surface
GO:0015629 actin cytoskeleton
GO:0016477 cell migration
GO:0021885 forebrain cell migration
GO:0030168 platelet activation
GO:0031100 animal organ regeneration
GO:0031668 cellular response to extracellular stimulus
GO:0032036 myosin heavy chain binding
GO:0032689 negative regulation of interferon-gamma production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032825 positive regulation of natural killer cell differentiation
GO:0032940 secretion by cell
GO:0033674 positive regulation of kinase activity
GO:0034101 erythrocyte homeostasis
GO:0034446 substrate adhesion-dependent cell spreading
GO:0035457 cellular response to interferon-alpha
GO:0042698 ovulation cycle
GO:0043066 negative regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043235 receptor complex
GO:0043491 protein kinase B signaling
GO:0043524 negative regulation of neuron apoptotic process
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0044228 host cell surface
GO:0045087 innate immune response
GO:0046718 viral entry into host cell
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048469 cell maturation
GO:0048549 positive regulation of pinocytosis
GO:0051250 negative regulation of lymphocyte activation
GO:0051897 positive regulation of protein kinase B signaling
GO:0060068 vagina development
GO:0070062 extracellular exosome
GO:0070301 cellular response to hydrogen peroxide
GO:0071222 cellular response to lipopolysaccharide
GO:0097028 dendritic cell differentiation
GO:0097350 neutrophil clearance
GO:1903902 positive regulation of viral life cycle
GO:2000669 negative regulation of dendritic cell apoptotic process

Diseases

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Interactions

64 interactions

InteractorPartnerSourcesPublicationsLink
AXLGAS6BioGRID, HPRD, MINT16362042 8621659 8939948 details
AXLGRB2BioGRID, HPRD, MINT18346204 9178760 details
AXLPLCG1HPRD, MINT9178760 details
AXLPIK3R1BioGRID, HPRD, MINT18346204 9178760 details
AXLSRCBioGRID, HPRD, MINT22327215 9178760 details
AXLEGFRBioGRID, IntAct25873175 27775700 details
AXLTNS2BioGRID, HPRD12470648 details
AXLLCKBioGRID, HPRD9178760 details
AXLPIK3R2BioGRID, HPRD9178760 details
AXLFBXO25BioGRID23940030 details
AXLRANBP9BioGRID, HPRD12470648 15964779 details
AXLTYRO3BioGRID15964779 details
AXLAXLBioGRID, HPRD27775700 31980649 9178760 details
AXLSOCS1BioGRID, HPRD12470648 29991678 details
AXLPIK3R3HPRD12470648 details
AXLNCK2HPRD12470648 details
AXLHSP90AB1BioGRID, IntAct22939624 31980649 details
AXLHSP90AA1BioGRID, IntAct22939624 23629654 31980649 details
AXLHSPA1ABioGRID, IntAct23629654 31980649 details
AXLCBLBioGRID, HPRD15958209 details
AXLTNK2BioGRID19815557 details
AXLERRFI1BioGRID19815557 details
AXLSTUB1BioGRID23629654 details
AXLABL2BioGRID18346204 details
AXLARRDC3BioGRID29416926 details
AXLSHC1HPRD8610109 details
AXLPTPN11HPRD15507525 details
AXLIL2RGHPRD16308569 details
AXLIL15RAHPRD16308569 details
AXLADAM10HPRD16227584 7822279 details
AXLSHC3HPRD8610109 details
AXLLOC102724334BioGRID, IntAct30021884 details
AXLMRPL17BioGRID, IntAct31980649 details
AXLIGF2BP3BioGRID, IntAct31980649 details
AXLMRPS14BioGRID, IntAct31980649 details
AXLBAG2BioGRID, IntAct31980649 details
AXLHSPA8BioGRID, IntAct31980649 details
AXLPABPC1BioGRID, IntAct31980649 details
AXLPABPC3BioGRID, IntAct31980649 details
AXLDSPBioGRID, IntAct31980649 details
AXLHSPA6BioGRID, IntAct31980649 details
AXLDNAJA1BioGRID, IntAct31980649 details
AXLSEC61BBioGRID, IntAct31980649 details
AXLMRPS34BioGRID, IntAct31980649 details
AXLPABPC4BioGRID, IntAct31980649 details
AXLPCBP1BioGRID, IntAct31980649 details
AXLPCBP2BioGRID, IntAct31980649 details
AXLCDC37BioGRID, IntAct31980649 details
AXLMRPS31BioGRID, IntAct31980649 details
AXLG3BP2BioGRID, IntAct31980649 details
AXLMRPS7BioGRID, IntAct31980649 details
AXLDNAJA2BioGRID, IntAct31980649 details
AXLRPLP1BioGRID, IntAct31980649 details
AXLSLC25A1BioGRID, IntAct31980649 details
AXLRPL39BioGRID, IntAct31980649 details
AXLPPIABioGRID, IntAct31980649 details
AXLRAD18BioGRID27377895 details
AXLRNF4BioGRID29180619 details
AXLWWP1BioGRID31340145 details
AXLNR3C1BioGRID31182584 details
AXLHSPA1BIntAct31980649 details
AXLELAVL1BioGRID19322201 details
AXLVIRMABioGRID29507755 details
AXLMTDHBioGRID22199357 details