Entity Details

Primary name BOK
Entity type gene
Source Source Link

Details

PrimaryID666
RefseqGeneNG_029488
SymbolBOK
NameBCL2 family apoptosis regulator BOK
Chromosome2
Location2q37.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-11-06
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsBOK_HUMAN

GO terms

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GOName
GO:0001836 release of cytochrome c from mitochondria
GO:0005102 signaling receptor binding
GO:0005634 nucleus
GO:0005640 nuclear outer membrane
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005743 mitochondrial inner membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006921 cellular component disassembly involved in execution phase of apoptosis
GO:0007420 brain development
GO:0008584 male gonad development
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0010506 regulation of autophagy
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031625 ubiquitin protein ligase binding
GO:0031901 early endosome membrane
GO:0031966 mitochondrial membrane
GO:0032588 trans-Golgi network membrane
GO:0033106 cis-Golgi network membrane
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0044877 protein-containing complex binding
GO:0046982 protein heterodimerization activity
GO:0048709 oligodendrocyte differentiation
GO:0051259 protein complex oligomerization
GO:0051400 BH domain binding
GO:0051402 neuron apoptotic process
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051902 negative regulation of mitochondrial depolarization
GO:0055038 recycling endosome membrane
GO:0060546 negative regulation of necroptotic process
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:1900119 positive regulation of execution phase of apoptosis
GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
GO:1901382 regulation of chorionic trophoblast cell proliferation
GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1903899 positive regulation of PERK-mediated unfolded protein response
GO:1904708 regulation of granulosa cell apoptotic process
GO:2001244 positive regulation of intrinsic apoptotic signaling pathway

Diseases

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Interactions

11 interactions