Entity Details

Primary name CAPN3
Entity type gene
Source Source Link

Details

PrimaryID825
RefseqGeneNG_008660
SymbolCAPN3
Namecalpain 3
Chromosome15
Location15q15.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-09-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCAN3_HUMAN

GO terms

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GOName
GO:0003824 catalytic activity
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
GO:0005622 intracellular anatomical structure
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006915 apoptotic process
GO:0007517 muscle organ development
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0008307 structural constituent of muscle
GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration
GO:0014850 response to muscle activity
GO:0030016 myofibril
GO:0030018 Z disc
GO:0030163 protein catabolic process
GO:0030239 myofibril assembly
GO:0030315 T-tubule
GO:0031402 sodium ion binding
GO:0031432 titin binding
GO:0031648 protein destabilization
GO:0032991 protein-containing complex
GO:0033234 negative regulation of protein sumoylation
GO:0042802 identical protein binding
GO:0043066 negative regulation of apoptotic process
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045214 sarcomere organization
GO:0045661 regulation of myoblast differentiation
GO:0045862 positive regulation of proteolysis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046716 muscle cell cellular homeostasis
GO:0050790 regulation of catalytic activity
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0051592 response to calcium ion
GO:0055103 ligase regulator activity
GO:0060090 molecular adaptor activity
GO:0061061 muscle structure development
GO:0065003 protein-containing complex assembly
GO:0070315 G1 to G0 transition involved in cell differentiation
GO:0071277 cellular response to calcium ion
GO:0071472 cellular response to salt stress
GO:0072657 protein localization to membrane
GO:0097264 self proteolysis
GO:1990092 calcium-dependent self proteolysis

Diseases

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Interactions

50 interactions

InteractorPartnerSourcesPublicationsLink
CAPN3TTNBioGRID, HPRD, IntAct, MINT10987085 20860623 23414517 8537379 9185618 9642272 9763216 details
CAPN3CRYABBioGRID, IntAct23414517 details
CAPN3POMPBioGRID, IntAct23414517 details
CAPN3C1QTNF9BioGRID, IntAct23414517 details
CAPN3AMOTBioGRID, IntAct23414517 details
CAPN3FNDC3BBioGRID, IntAct23414517 details
CAPN3CMYA5BioGRID, IntAct23414517 details
CAPN3MYBPHBioGRID, IntAct23414517 details
CAPN3MYBPC1BioGRID, IntAct23414517 details
CAPN3MMP2BioGRID, IntAct23414517 details
CAPN3PSMC3BioGRID, IntAct23414517 details
CAPN3PREPLBioGRID, IntAct23414517 details
CAPN3RNF167BioGRID, IntAct23414517 details
CAPN3PSMD1BioGRID, IntAct23414517 details
CAPN3CAPN3BioGRID, HPRD, IntAct, MINT15073171 24846670 32296183 details
CAPN3NTAQ1BioGRID, IntAct25416956 32296183 details
CAPN3OSGIN1BioGRID, IntAct25416956 31515488 details
CAPN3TFCP2BioGRID, IntAct26871637 details
CAPN3EXOC8BioGRID, IntAct32296183 details
CAPN3ZNF410IntAct32296183 details
CAPN3VEZF1IntAct32296183 details
CAPN3BYSLIntAct32296183 details
CAPN3EHHADHIntAct32296183 details
CAPN3GTPBP3BioGRID, IntAct32296183 details
CAPN3CCDC102BBioGRID, IntAct32296183 details
CAPN3RUFY3BioGRID, IntAct32296183 details
CAPN3KANK2BioGRID, IntAct32296183 details
CAPN3MAP1LC3CBioGRID, IntAct32296183 details
CAPN3TRIM63BioGRID, IntAct31391242 details
CAPN3CASP6IntAct32814053 details
CAPN3CHATIntAct32814053 details
CAPN3FGFR3IntAct32814053 details
CAPN3GSNIntAct32814053 details
CAPN3LAMP2IntAct32814053 details
CAPN3RANIntAct32814053 details
CAPN3UBQLN1IntAct32814053 details
CAPN3SH3GLB1IntAct32814053 details
CAPN3PRPF40AIntAct32814053 details
CAPN3NECAB2BioGRID, HPRD16189514 details
CAPN3FLNCBioGRID, HPRD14506720 details
CAPN3CEP76BioGRID26871637 details
CAPN3TRIM55BioGRID31391242 details
CAPN3TRIM54IntAct31391242 details
CAPN3FXR1MINT21653829 details
CAPN3UBE3AMINT21653829 details
CAPN3YWHAQHPRD15324660 details
CAPN3DYSFHPRD15827562 details
CAPN3H3-4BioGRID, IntAct30021884 details
CAPN3YARS2BioGRID26344197 details
CAPN3PSMA3BioGRID30009671 details