Entity Details

Primary name DHB12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ53GQ0
EntryNameDHB12_HUMAN
FullNameVery-long-chain 3-oxoacyl-CoA reductase
TaxID9606
Evidenceevidence at protein level
Length312
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesHSD17B12

GO terms

Show/Hide Table
GOName
GO:0001968 fibronectin binding
GO:0005518 collagen binding
GO:0005789 endoplasmic reticulum membrane
GO:0006633 fatty acid biosynthetic process
GO:0006703 estrogen biosynthetic process
GO:0008201 heparin binding
GO:0009923 fatty acid elongase complex
GO:0010811 positive regulation of cell-substrate adhesion
GO:0016021 integral component of membrane
GO:0030198 extracellular matrix organization
GO:0031012 extracellular matrix
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process
GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
GO:0050062 long-chain-fatty-acyl-CoA reductase activity
GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity
GO:0102339 3-oxo-arachidoyl-CoA reductase activity
GO:0102340 3-oxo-behenoyl-CoA reductase activity
GO:0102341 3-oxo-lignoceroyl-CoA reductase activity
GO:0102342 3-oxo-cerotoyl-CoA reductase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Endoplasmic reticulum membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table