Entity Details

Primary name EDEM1
Entity type gene
Source Source Link

Details

PrimaryID9695
RefseqGene
SymbolEDEM1
NameER degradation enhancing alpha-mannosidase like protein 1
Chromosome3
Location3p26.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-11-30
ModificationDate2021-06-12

Ontological Relatives

UniProt IDsEDEM1_HUMAN

GO terms

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GOName
GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 calcium ion binding
GO:0005783 endoplasmic reticulum
GO:0005975 carbohydrate metabolic process
GO:0016235 aggresome
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0036498 IRE1-mediated unfolded protein response
GO:0036510 trimming of terminal mannose on C branch
GO:0044322 endoplasmic reticulum quality control compartment
GO:0045047 protein targeting to ER
GO:0051787 misfolded protein binding
GO:0097466 ubiquitin-dependent glycoprotein ERAD pathway
GO:1904154 positive regulation of retrograde protein transport, ER to cytosol
GO:1904382 mannose trimming involved in glycoprotein ERAD pathway

Diseases

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Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
EDEM1SSR1BioGRID, MINT17380188 details
EDEM1CANXBioGRID, HPRD, IntAct12610305 17360537 21632540 22119785 24910992 details
EDEM1SEL1LBioGRID19524542 21632540 24910992 details
EDEM1ASGR2BioGRID21062743 details
EDEM1RHOBioGRID19934218 details
EDEM1DNAJC10BioGRID21632540 details
EDEM1SEC61BBioGRID17360537 details
EDEM1DERL1BioGRID17360537 details
EDEM1DERL2BioGRID17360537 details
EDEM1ASGR1BioGRID23233672 details
EDEM1SQSTM1BioGRID24664425 details
EDEM1HLA-BBioGRID25132672 details
EDEM1SHHBioGRID24910992 details
EDEM1SERPINA1BioGRID30021839 details
EDEM1BZW1BioGRID, IntAct17353931 details
EDEM1ACSL4BioGRID, IntAct26496610 details
EDEM1PSMD14BioGRID, IntAct26496610 details
EDEM1PNISRBioGRID, IntAct26496610 details
EDEM1CHD9BioGRID, IntAct26496610 details
EDEM1PHF6BioGRID, IntAct26496610 details
EDEM1SUFUBioGRID, IntAct26496610 details
EDEM1P4HBBioGRID, IntAct26496610 details
EDEM1LYZL1BioGRID, IntAct28514442 details
EDEM1LYZL2BioGRID, IntAct28514442 details
EDEM1MPPE1BioGRID, IntAct28514442 details
EDEM1GALNT6BioGRID, IntAct28514442 details
EDEM1ZACNBioGRID, IntAct26186194 28514442 details
EDEM1NAAABioGRID, IntAct26186194 28514442 details
EDEM1MTCH1BioGRID, IntAct22119785 details
EDEM1ESYT1BioGRID, IntAct22119785 details
EDEM1UBQLN2BioGRID, IntAct22119785 details
EDEM1MMS19BioGRID22678362 details
EDEM1EGFRBioGRID28065597 details
EDEM1LOXL3BioGRID28514442 details
EDEM1MTM1BioGRID28675297 details
EDEM1FBXO6BioGRID32409323 details
EDEM1ELAVL1BioGRID19322201 details