Entity Details

Primary name ANO1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5XXA6
EntryNameANO1_HUMAN
FullNameAnoctamin-1
TaxID9606
Evidenceevidence at protein level
Length986
SequenceStatuscomplete
DateCreated2007-05-29
DateModified2021-06-02

Ontological Relatives

GenesANO1

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005227 calcium activated cation channel activity
GO:0005229 intracellular calcium activated chloride channel activity
GO:0005247 voltage-gated chloride channel activity
GO:0005254 chloride channel activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006812 cation transport
GO:0006821 chloride transport
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007275 multicellular organism development
GO:0015111 iodide transmembrane transporter activity
GO:0015705 iodide transport
GO:0016324 apical plasma membrane
GO:0034220 ion transmembrane transport
GO:0034605 cellular response to heat
GO:0034707 chloride channel complex
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042803 protein homodimerization activity
GO:0045121 membrane raft
GO:0046872 metal ion binding
GO:0050965 detection of temperature stimulus involved in sensory perception of pain
GO:0055085 transmembrane transport
GO:0070062 extracellular exosome
GO:1901653 cellular response to peptide
GO:1902476 chloride transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR007632 AnoctaminFamilyFamily
IPR031287 Anoctamin-1FamilyFamily
IPR032394 Anoctamin, dimerisation domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB04941 CrofelemerDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ANO1_HUMANCFTR_HUMANI2D22178883 details