Entity Details

Primary name S27A1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6PCB7
EntryNameS27A1_HUMAN
FullNameLong-chain fatty acid transport protein 1
TaxID9606
Evidenceevidence at protein level
Length646
SequenceStatuscomplete
DateCreated2005-11-08
DateModified2021-06-02

Ontological Relatives

GenesSLC27A1

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0001579 medium-chain fatty acid transport
GO:0004467 long-chain fatty acid-CoA ligase activity
GO:0005324 long-chain fatty acid transporter activity
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006646 phosphatidylethanolamine biosynthetic process
GO:0006654 phosphatidic acid biosynthetic process
GO:0006655 phosphatidylglycerol biosynthetic process
GO:0006656 phosphatidylcholine biosynthetic process
GO:0006659 phosphatidylserine biosynthetic process
GO:0006661 phosphatidylinositol biosynthetic process
GO:0009409 response to cold
GO:0009925 basal plasma membrane
GO:0010867 positive regulation of triglyceride biosynthetic process
GO:0015225 biotin transmembrane transporter activity
GO:0015245 fatty acid transmembrane transporter activity
GO:0015562 efflux transmembrane transporter activity
GO:0015878 biotin transport
GO:0015909 long-chain fatty acid transport
GO:0015911 long-chain fatty acid import across plasma membrane
GO:0016020 membrane
GO:0019222 regulation of metabolic process
GO:0031652 positive regulation of heat generation
GO:0031957 very long-chain fatty acid-CoA ligase activity
GO:0032049 cardiolipin biosynthetic process
GO:0032868 response to insulin
GO:0033211 adiponectin-activated signaling pathway
GO:0044381 glucose import in response to insulin stimulus
GO:0044539 long-chain fatty acid import into cell
GO:0047676 arachidonate-CoA ligase activity
GO:0071072 negative regulation of phospholipid biosynthetic process
GO:0071902 positive regulation of protein serine/threonine kinase activity
GO:0090434 oleoyl-CoA ligase activity
GO:0140115 export across plasma membrane
GO:0150104 transport across blood-brain barrier
GO:1901480 oleate transmembrane transporter activity
GO:1905135 biotin import across plasma membrane
GO:1990379 lipid transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Endomembrane system

Domains

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DomainNameCategoryType
IPR000873 AMP-dependent synthetase/ligaseDomainDomain
IPR020845 AMP-binding, conserved siteSiteConserved site
IPR025110 AMP-binding enzyme, C-terminal domainDomainDomain
IPR030308 Fatty acid transport protein 1FamilyFamily
IPR042099 ANL, N-terminal domainFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
S27A1_HUMANRPE65_HUMANBioGRID20356843 details