Entity Details

Primary name LARP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6PKG0
EntryNameLARP1_HUMAN
FullNameLa-related protein 1
TaxID9606
Evidenceevidence at protein level
Length1096
SequenceStatuscomplete
DateCreated2005-08-16
DateModified2021-06-02

Ontological Relatives

GenesLARP1

GO terms

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GOName
GO:0000339 RNA cap binding
GO:0000340 RNA 7-methylguanosine cap binding
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005737 cytoplasm
GO:0006413 translational initiation
GO:0008190 eukaryotic initiation factor 4E binding
GO:0008283 cell population proliferation
GO:0008494 translation activator activity
GO:0010494 cytoplasmic stress granule
GO:0010608 posttranscriptional regulation of gene expression
GO:0016020 membrane
GO:0016239 positive regulation of macroautophagy
GO:0017148 negative regulation of translation
GO:0031369 translation initiation factor binding
GO:0031929 TOR signaling
GO:0038202 TORC1 signaling
GO:0043024 ribosomal small subunit binding
GO:0045070 positive regulation of viral genome replication
GO:0045296 cadherin binding
GO:0045947 negative regulation of translational initiation
GO:0045948 positive regulation of translational initiation
GO:0048027 mRNA 5'-UTR binding
GO:0048255 mRNA stabilization
GO:0072752 cellular response to rapamycin
GO:1990928 response to amino acid starvation

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic granule

Domains

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DomainNameCategoryType
IPR006607 Protein of unknown function DM15RepeatRepeat
IPR006630 La-type HTH domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

36 interactions

InteractorPartnerSourcesPublicationsLink
LARP1_HUMANB2CL1_HUMANBioGRID, MINT21900206 details
LARP1_HUMANTNNT1_HUMANBioGRID, MINT21900206 details
LARP1_HUMANCSK21_HUMANBioGRID, IntAct22113938 details
LARP1_HUMANSRPK1_HUMANBioGRID, IntAct23602568 details
LARP1_HUMANKASH5_HUMANBioGRID, IntAct25416956 details
LARP1_HUMAN1433Z_HUMANBioGRID, IntAct, MINT15161933 15324660 17353931 details
LARP1_HUMANEIF1B_HUMANIntAct17353931 details
LARP1_HUMANDCLK1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANSI1L1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANSRGP2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANGGYF1_HUMANIntActunassigned1312 details
LARP1_HUMANKCTD3_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANPPM1H_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANRTKN_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANDEN1A_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANKSR1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANSPD2A_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANZN638_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANIF4E2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANMAST3_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANMAGI1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANTESK2_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANKI13B_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANLRFN1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANCING_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANLIMA1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANZBT21_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANCBY1_HUMANBioGRID, IntAct27173435 unassigned1312 details
LARP1_HUMANTS101_HUMANBioGRID19542561 details
LARP1_HUMANNFX1_HUMANBioGRID17267499 31059266 32460013 details
LARP1_HUMAN1433E_HUMANBioGRID17979178 19608861 details
LARP1_HUMANU2AF2_HUMANBioGRID26641092 details
LARP1_HUMANRPTOR_HUMANBioGRID25940091 details
LARP1_HUMANMTOR_HUMANBioGRID25940091 details
LARP1_HUMANLST8_HUMANBioGRID25940091 details
LARP1_HUMANPABP1_HUMANBioGRID25940091 29395067 details