Entity Details

Primary name RSPO2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6UXX9
EntryNameRSPO2_HUMAN
FullNameR-spondin-2
TaxID9606
Evidenceevidence at protein level
Length243
SequenceStatuscomplete
DateCreated2006-05-16
DateModified2021-06-02

Ontological Relatives

GenesRSPO2

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0008201 heparin binding
GO:0009986 cell surface
GO:0016055 Wnt signaling pathway
GO:0030177 positive regulation of Wnt signaling pathway
GO:0030282 bone mineralization
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0042489 negative regulation of odontogenesis of dentin-containing tooth
GO:0060173 limb development
GO:0060437 lung growth
GO:0060441 epithelial tube branching involved in lung morphogenesis
GO:0060535 trachea cartilage morphogenesis
GO:0071542 dopaminergic neuron differentiation
GO:0090263 positive regulation of canonical Wnt signaling pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR006212 Furin-like repeatRepeatRepeat
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR042993 R-spondin-2/4FamilyFamily
IPR043601 R-spondin, Fu-CRD domainDomainDomain

Diseases

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