Entity Details

Primary name S36A1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z2H8
EntryNameS36A1_HUMAN
FullNameProton-coupled amino acid transporter 1
TaxID9606
Evidenceevidence at protein level
Length476
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesSLC36A1

GO terms

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GOName
GO:0003333 amino acid transmembrane transport
GO:0005280 amino acid:proton symporter activity
GO:0005368 taurine transmembrane transporter activity
GO:0005765 lysosomal membrane
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0006811 ion transport
GO:0006865 amino acid transport
GO:0015171 amino acid transmembrane transporter activity
GO:0015180 L-alanine transmembrane transporter activity
GO:0015187 glycine transmembrane transporter activity
GO:0015193 L-proline transmembrane transporter activity
GO:0015734 taurine transport
GO:0015808 L-alanine transport
GO:0015816 glycine transport
GO:0015824 proline transport
GO:0016021 integral component of membrane
GO:0022858 alanine transmembrane transporter activity
GO:0032328 alanine transport
GO:0035524 proline transmembrane transport
GO:0089718 amino acid import across plasma membrane
GO:1902600 proton transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane
Lysosome membrane

Domains

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DomainNameCategoryType
IPR013057 Amino acid transporter, transmembrane domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00145 GlycineDrugbanksmall molecule
DB00160 AlanineDrugbanksmall molecule
DB00563 MethotrexateDrugbanksmall molecule
DB00659 AcamprosateDrugbanksmall molecule
DB01080 VigabatrinDrugbanksmall molecule
DB01956 TaurineDrugbanksmall molecule
DB02530 gamma-Aminobutyric acidDrugbanksmall molecule
DB02853 D-ProlineSwissprotsmall molecule
DB06554 GaboxadolSwissprotsmall molecule
DB08835 Spaglumic AcidDrugbanksmall molecule
DB08847 HydroxyprolineSwissprotsmall molecule
DB08849 Nipecotic acidSwissprotsmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
S36A1_HUMANA4_HUMANIntAct32814053 details
S36A1_HUMANTARG1_HUMANBioGRID32296183 details