Entity Details

Primary name MYH14_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7Z406
EntryNameMYH14_HUMAN
FullNameMyosin-14
TaxID9606
Evidenceevidence at protein level
Length1995
SequenceStatuscomplete
DateCreated2005-07-19
DateModified2021-06-02

Ontological Relatives

GenesMYH14

GO terms

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GOName
GO:0000146 microfilament motor activity
GO:0001725 stress fiber
GO:0003009 skeletal muscle contraction
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0005903 brush border
GO:0007519 skeletal muscle tissue development
GO:0007605 sensory perception of sound
GO:0008360 regulation of cell shape
GO:0016020 membrane
GO:0016460 myosin II complex
GO:0016887 ATP hydrolysis activity
GO:0019228 neuronal action potential
GO:0030048 actin filament-based movement
GO:0030426 growth cone
GO:0031032 actomyosin structure organization
GO:0042641 actomyosin
GO:0051015 actin filament binding
GO:0070062 extracellular exosome
GO:0070584 mitochondrion morphogenesis
GO:0071625 vocalization behavior
GO:0097513 myosin II filament

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR001609 Myosin head, motor domainDomainDomain
IPR002928 Myosin tailDomainDomain
IPR004009 Myosin, N-terminal, SH3-likeDomainDomain
IPR008989 Myosin S1 fragment, N-terminalFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036961 Kinesin motor domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01944 (S)-blebbistatinDrugbanksmall molecule
DB03126 Mant-AdpDrugbanksmall molecule
DB04444 Tetrafluoroaluminate IonDrugbanksmall molecule
DB07468 (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-oneDrugbanksmall molecule
DB07469 (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-oneDrugbanksmall molecule
DB07470 (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-oneDrugbanksmall molecule
DB08276 trifluoro-[hydroxy-[hydroxy-[2-(N-methyl-2-nitro-anilino)ethoxy]phosphoryl]oxy-phosphoryl]oxy-beryllium(1-)Drugbanksmall molecule