Entity Details

Primary name DCP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IU60
EntryNameDCP2_HUMAN
FullNamem7GpppN-mRNA hydrolase
TaxID9606
Evidenceevidence at protein level
Length420
SequenceStatuscomplete
DateCreated2005-03-01
DateModified2021-06-02

Ontological Relatives

GenesDCP2

GO terms

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GOName
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000932 P-body
GO:0004534 5'-3' exoribonuclease activity
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006402 mRNA catabolic process
GO:0016442 RISC complex
GO:0030054 cell junction
GO:0030145 manganese ion binding
GO:0032211 negative regulation of telomere maintenance via telomerase
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0043488 regulation of mRNA stability
GO:0043928 exonucleolytic catabolism of deadenylated mRNA
GO:0050072 m7G(5')pppN diphosphatase activity
GO:0070034 telomerase RNA binding
GO:0071044 histone mRNA catabolic process
GO:1904872 regulation of telomerase RNA localization to Cajal body

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000086 NUDIX hydrolase domainDomainDomain
IPR007722 mRNA decapping protein 2, Box A domainDomainDomain
IPR015797 NUDIX hydrolase-like domain superfamilyFamilyHomologous superfamily
IPR020084 NUDIX hydrolase, conserved siteSiteConserved site
IPR036189 mRNA decapping protein 2, Box A domain superfamilyFamilyHomologous superfamily
IPR044099 mRNA decapping enzyme 2 , NUDIX hydrolase domainDomainDomain

Diseases

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