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Entity Details
Primary name
VRK3_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q8IV63
EntryName
VRK3_HUMAN
FullName
Inactive serine/threonine-protein kinase VRK3
TaxID
9606
Evidence
evidence at protein level
Length
474
SequenceStatus
complete
DateCreated
2003-10-10
DateModified
2021-06-02
Ontological Relatives
Genes
VRK3
GO terms
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GO
Name
GO:0004674
protein serine/threonine kinase activity
GO:0005524
ATP binding
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005730
nucleolus
GO:0005737
cytoplasm
GO:0018105
peptidyl-serine phosphorylation
GO:0019903
protein phosphatase binding
GO:0032516
positive regulation of phosphoprotein phosphatase activity
GO:0043231
intracellular membrane-bounded organelle
GO:0070373
negative regulation of ERK1 and ERK2 cascade
Subcellular Location
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Subcellular Location
Nucleus
Domains
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Domain
Name
Category
Type
IPR000719
Protein kinase domain
Domain
Domain
IPR011009
Protein kinase-like domain superfamily
Family
Homologous superfamily
IPR026870
Zinc-ribbon domain
Domain
Domain
Diseases
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Drugs
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Interactions
16 interactions
Interactor
Partner
Sources
Publications
Link
VRK3_HUMAN
TS101_HUMAN
IntAct
19549727
details
VRK3_HUMAN
CSK2B_HUMAN
BioGRID, MINT
21900206
details
VRK3_HUMAN
PLK1_HUMAN
BioGRID, MINT
21900206
details
VRK3_HUMAN
FBX7_HUMAN
BioGRID
27503909
details
VRK3_HUMAN
OGT1_HUMAN
BioGRID
32994395
details
VRK3_HUMAN
DSG1_HUMAN
IntAct
17353931
details
VRK3_HUMAN
RAN_HUMAN
IntAct
18617507
details
VRK3_HUMAN
NUCL_HUMAN
BioGRID
28927264
details
VRK3_HUMAN
NPM_HUMAN
BioGRID
28927264
details
VRK3_HUMAN
P53_HUMAN
BioGRID
28927264
32807901
details
VRK3_HUMAN
XRCC5_HUMAN
BioGRID
28927264
details
VRK3_HUMAN
CCNB1_HUMAN
BioGRID
28927264
details
VRK3_HUMAN
BAF_HUMAN
BioGRID
28927264
details
VRK3_HUMAN
PARP1_HUMAN
BioGRID
28927264
details
VRK3_HUMAN
HSP74_HUMAN
BioGRID
28927264
details
VRK3_HUMAN
THOC4_HUMAN
BioGRID
28927264
details
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