Entity Details

Primary name SULF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IWU5
EntryNameSULF2_HUMAN
FullNameExtracellular sulfatase Sulf-2
TaxID9606
Evidenceevidence at protein level
Length870
SequenceStatuscomplete
DateCreated2003-07-19
DateModified2021-06-02

Ontological Relatives

GenesSULF2

GO terms

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GOName
GO:0001822 kidney development
GO:0002063 chondrocyte development
GO:0003094 glomerular filtration
GO:0004065 arylsulfatase activity
GO:0005509 calcium ion binding
GO:0005539 glycosaminoglycan binding
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005795 Golgi stack
GO:0005886 plasma membrane
GO:0008449 N-acetylglucosamine-6-sulfatase activity
GO:0009611 response to wounding
GO:0009986 cell surface
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0014846 esophagus smooth muscle contraction
GO:0030177 positive regulation of Wnt signaling pathway
GO:0030201 heparan sulfate proteoglycan metabolic process
GO:0032836 glomerular basement membrane development
GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway
GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway
GO:0048706 embryonic skeletal system development
GO:0051216 cartilage development
GO:0060348 bone development
GO:0060384 innervation
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0097421 liver regeneration
GO:2000345 regulation of hepatocyte proliferation

Subcellular Location

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Subcellular Location
Cell surface
Endoplasmic reticulum
Golgi apparatus

Domains

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DomainNameCategoryType
IPR000917 Sulfatase, N-terminalDomainDomain
IPR014615 Extracellular sulfataseFamilyFamily
IPR017850 Alkaline-phosphatase-like, core domain superfamilyFamilyHomologous superfamily
IPR024607 Sulfatase, conserved siteSiteConserved site
IPR024609 Extracellular sulfatase, C-terminalDomainDomain

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink