Entity Details

Primary name KCNK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00180
EntryNameKCNK1_HUMAN
FullNamePotassium channel subfamily K member 1
TaxID9606
Evidenceevidence at protein level
Length336
SequenceStatuscomplete
DateCreated2001-02-21
DateModified2021-06-02

Ontological Relatives

GenesKCNK1

GO terms

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GOName
GO:0005242 inward rectifier potassium channel activity
GO:0005267 potassium channel activity
GO:0005272 sodium channel activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006813 potassium ion transport
GO:0008076 voltage-gated potassium channel complex
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0022841 potassium ion leak channel activity
GO:0030322 stabilization of membrane potential
GO:0030425 dendrite
GO:0031526 brush border membrane
GO:0034705 potassium channel complex
GO:0035094 response to nicotine
GO:0035725 sodium ion transmembrane transport
GO:0042802 identical protein binding
GO:0043204 perikaryon
GO:0043231 intracellular membrane-bounded organelle
GO:0055037 recycling endosome
GO:0060075 regulation of resting membrane potential
GO:0061337 cardiac conduction
GO:0071805 potassium ion transmembrane transport
GO:0097060 synaptic membrane
GO:1902937 inward rectifier potassium channel complex

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell junction
Cell membrane
Cell projection
Cytoplasmic vesicle
Perikaryon
Recycling endosome

Domains

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DomainNameCategoryType
IPR001779 Two pore domain potassium channel, TWIK-1FamilyFamily
IPR003092 Two pore domain potassium channel, TASK familyFamilyFamily
IPR003280 Two pore domain potassium channelFamilyFamily
IPR005408 Two pore domain potassium channel, TWIK familyFamilyFamily
IPR013099 Potassium channel domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00308 IbutilideDrugbanksmall molecule
DB00908 QuinidineDrugbanksmall molecule
DB01346 Quinidine barbiturateDrugbanksmall molecule