Entity Details

Primary name NDUS8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00217
EntryNameNDUS8_HUMAN
FullNameNADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length210
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesNDUFS8

GO terms

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GOName
GO:0005739 mitochondrion
GO:0005747 mitochondrial respiratory chain complex I
GO:0005759 mitochondrial matrix
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0006979 response to oxidative stress
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0009060 aerobic respiration
GO:0032981 mitochondrial respiratory chain complex I assembly
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR010226 NADH-quinone oxidoreductase, chain IFamilyFamily
IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domainDomainDomain
IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved siteSiteConserved site

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule

Interactions

5 interactions