Entity Details

Primary name EDA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92838
EntryNameEDA_HUMAN
FullNameEctodysplasin-A
TaxID9606
Evidenceevidence at protein level
Length391
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesEDA

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005123 death receptor binding
GO:0005164 tumor necrosis factor receptor binding
GO:0005581 collagen trimer
GO:0005615 extracellular space
GO:0005789 endoplasmic reticulum membrane
GO:0005811 lipid droplet
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006955 immune response
GO:0007160 cell-matrix adhesion
GO:0010467 gene expression
GO:0010628 positive regulation of gene expression
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0030154 cell differentiation
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0038177 death receptor agonist activity
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043231 intracellular membrane-bounded organelle
GO:0043473 pigmentation
GO:0045177 apical part of cell
GO:0048018 receptor ligand activity
GO:0048513 animal organ development
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060662 salivary gland cavitation
GO:0060789 hair follicle placode formation
GO:0061153 trachea gland development
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901222 regulation of NIK/NF-kappaB signaling
GO:1901224 positive regulation of NIK/NF-kappaB signaling

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR006052 Tumour necrosis factor domainDomainDomain
IPR008983 Tumour necrosis factor-like domain superfamilyFamilyHomologous superfamily

Diseases

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