Entity Details

Primary name ESAM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96AP7
EntryNameESAM_HUMAN
FullNameEndothelial cell-selective adhesion molecule
TaxID9606
Evidenceevidence at protein level
Length390
SequenceStatuscomplete
DateCreated2005-06-21
DateModified2021-06-02

Ontological Relatives

GenesESAM

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005923 bicellular tight junction
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0016021 integral component of membrane
GO:0030833 regulation of actin filament polymerization
GO:0032991 protein-containing complex
GO:0034613 cellular protein localization
GO:0035633 maintenance of blood-brain barrier
GO:0050900 leukocyte migration
GO:0070830 bicellular tight junction assembly
GO:0098609 cell-cell adhesion
GO:0098632 cell-cell adhesion mediator activity
GO:2000249 regulation of actin cytoskeleton reorganization

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR042757 Endothelial cell-selective adhesion moleculeFamilyFamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ESAM_HUMANESAM_HUMANBioGRID, IntAct21982860 details
ESAM_HUMANTTMP_HUMANBioGRID, IntAct32296183 details
ESAM_HUMANBI1_HUMANBioGRID, IntAct32296183 details