Entity Details

Primary name H17B6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14756
EntryNameH17B6_HUMAN
FullName17-beta-hydroxysteroid dehydrogenase type 6
TaxID9606
Evidenceevidence at protein level
Length317
SequenceStatuscomplete
DateCreated2007-09-11
DateModified2021-06-02

Ontological Relatives

GenesHSD17B6

GO terms

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GOName
GO:0003824 catalytic activity
GO:0004745 NAD-retinol dehydrogenase activity
GO:0005783 endoplasmic reticulum
GO:0006702 androgen biosynthetic process
GO:0006710 androgen catabolic process
GO:0009055 electron transfer activity
GO:0016491 oxidoreductase activity
GO:0031901 early endosome membrane
GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity
GO:0047023 androsterone dehydrogenase activity
GO:0047024 5alpha-androstane-3beta,17beta-diol dehydrogenase activity
GO:0047035 testosterone dehydrogenase (NAD+) activity
GO:0047044 androstan-3-alpha,17-beta-diol dehydrogenase activity
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0062175 brexanolone catabolic process
GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity

Subcellular Location

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Subcellular Location
Early endosome membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR002347 Short-chain dehydrogenase/reductase SDRFamilyFamily
IPR020904 Short-chain dehydrogenase/reductase, conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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InteractorPartnerSourcesPublicationsLink