Entity Details

Primary name CI072_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96LT7
EntryNameCI072_HUMAN
FullNameGuanine nucleotide exchange C9orf72
TaxID9606
Evidenceevidence at protein level
Length481
SequenceStatuscomplete
DateCreated2005-07-19
DateModified2021-06-02

Ontological Relatives

GenesC9orf72

GO terms

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GOName
GO:0000932 P-body
GO:0001933 negative regulation of protein phosphorylation
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005764 lysosome
GO:0005768 endosome
GO:0005776 autophagosome
GO:0005829 cytosol
GO:0006897 endocytosis
GO:0006914 autophagy
GO:0010494 cytoplasmic stress granule
GO:0010506 regulation of autophagy
GO:0016239 positive regulation of macroautophagy
GO:0030425 dendrite
GO:0031267 small GTPase binding
GO:0031965 nuclear membrane
GO:0032045 guanyl-nucleotide exchange factor complex
GO:0034063 stress granule assembly
GO:0043204 perikaryon
GO:0043231 intracellular membrane-bounded organelle
GO:0044295 axonal growth cone
GO:0044304 main axon
GO:0048675 axon extension
GO:0090543 Flemming body
GO:0110053 regulation of actin filament organization
GO:1902774 late endosome to lysosome transport
GO:1903432 regulation of TORC1 signaling
GO:2000785 regulation of autophagosome assembly

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Cytoplasmic vesicle
Endosome
Lysosome
Nucleus
Nucleus membrane
Perikaryon
Secreted

Domains

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DomainNameCategoryType
IPR027819 Guanine nucleotide exchange C9orf72FamilyFamily

Diseases

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Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
CI072_HUMANEI2BB_HUMANBioGRID, IntAct, MINT21516116 25416956 32296183 details
CI072_HUMANSRPK1_HUMANBioGRID, IntAct23602568 details
CI072_HUMANCRX_HUMANBioGRID, IntAct25416956 details
CI072_HUMANREL_HUMANBioGRID, IntAct25416956 details
CI072_HUMANNMI_HUMANBioGRID, IntAct25416956 details
CI072_HUMANSMCR8_HUMANBioGRID, IntAct, MINT, UniProt27103069 27107012 27617292 29950492 30669939 32296183 details
CI072_HUMANCOIL_HUMANBioGRID, IntAct32296183 details
CI072_HUMANVRTN_HUMANBioGRID, IntAct32296183 details
CI072_HUMANHM20A_HUMANBioGRID, IntAct32296183 details
CI072_HUMANTRI74_HUMANIntAct32296183 details
CI072_HUMANPOP7_HUMANBioGRID, IntAct32296183 details
CI072_HUMANATG13_HUMANBioGRID, IntAct, UniProt27334615 27617292 29950492 30669939 details
CI072_HUMANRAB1A_HUMANIntAct27334615 details
CI072_HUMANWDR41_HUMANBioGRID, MINT, UniProt27103069 27617292 29950492 30669939 details
CI072_HUMANA4_HUMANBioGRID21832049 details
CI072_HUMANCI072_HUMANBioGRID30669939 details
CI072_HUMANTRI73_HUMANBioGRID32296183 details
CI072_HUMANSYN3_HUMANBioGRID32296183 details
CI072_HUMANRBCC1_HUMANBioGRID, IntAct, UniProt20562859 27334615 29950492 30669939 details
CI072_HUMANULK1_HUMANBioGRID, IntAct, MINT, UniProt27103069 27334615 27617292 29950492 30669939 details
CI072_HUMANRB39B_HUMANBioGRID, MINT27103069 27617292 details
CI072_HUMANRAB8B_HUMANBioGRID27103069 details
CI072_HUMANRB33A_HUMANBioGRID27103069 details
CI072_HUMANRAB38_HUMANBioGRID27103069 details
CI072_HUMANRB39A_HUMANBioGRID27103069 details
CI072_HUMANRAB6A_HUMANBioGRID27103069 details
CI072_HUMANRAB12_HUMANBioGRID27103069 details
CI072_HUMANRAB25_HUMANBioGRID27103069 details
CI072_HUMANTBKB1_HUMANBioGRID27103069 details
CI072_HUMANTANK_HUMANBioGRID27103069 details
CI072_HUMANAZI2_HUMANBioGRID27103069 details
CI072_HUMANSYIC_HUMANBioGRID30669939 details
CI072_HUMANATGA1_HUMANBioGRID27617292 30669939 details
CI072_HUMANST7_HUMANBioGRID29395067 details