Entity Details

Primary name NOX5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96PH1
EntryNameNOX5_HUMAN
FullNameNADPH oxidase 5
TaxID9606
Evidenceevidence at protein level
Length765
SequenceStatuscomplete
DateCreated2006-03-07
DateModified2021-06-02

Ontological Relatives

GenesNOX5

GO terms

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GOName
GO:0000293 ferric-chelate reductase activity
GO:0001525 angiogenesis
GO:0001819 positive regulation of cytokine production
GO:0001935 endothelial cell proliferation
GO:0005509 calcium ion binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0015252 proton channel activity
GO:0016021 integral component of membrane
GO:0016175 superoxide-generating NAD(P)H oxidase activity
GO:0020037 heme binding
GO:0033215 reductive iron assimilation
GO:0034599 cellular response to oxidative stress
GO:0042554 superoxide anion generation
GO:0043012 regulation of fusion of sperm to egg plasma membrane
GO:0050660 flavin adenine dinucleotide binding
GO:0050661 NADP binding
GO:0061640 cytoskeleton-dependent cytokinesis
GO:1902600 proton transmembrane transport
GO:2000379 positive regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Endoplasmic reticulum
Membrane

Domains

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DomainNameCategoryType
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR013112 FAD-binding 8DomainDomain
IPR013121 Ferric reductase, NAD binding domainDomainDomain
IPR013130 Ferric reductase transmembrane component-like domainDomainDomain
IPR017927 FAD-binding domain, ferredoxin reductase-typeDomainDomain
IPR017938 Riboflavin synthase-like beta-barrelFamilyHomologous superfamily
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domainFamilyHomologous superfamily

Diseases

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