Entity Details

Primary name CSF3R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99062
EntryNameCSF3R_HUMAN
FullNameGranulocyte colony-stimulating factor receptor
TaxID9606
Evidenceevidence at protein level
Length836
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesCSF3R

GO terms

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GOName
GO:0004896 cytokine receptor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006952 defense response
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0009897 external side of plasma membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0030593 neutrophil chemotaxis
GO:0038023 signaling receptor activity
GO:0043235 receptor complex
GO:0045637 regulation of myeloid cell differentiation
GO:0051916 granulocyte colony-stimulating factor binding
GO:0097186 amelogenesis

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR003529 Long hematopoietin receptor, Gp130 family 2, conserved siteSiteConserved site
IPR003961 Fibronectin type IIIDomainDomain
IPR010457 Immunoglobulin C2-set-like, ligand-bindingDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00019 PegfilgrastimDrugbankbiotech
DB00099 FilgrastimDrugbankbiotech
DB05249 FavIdDrugbanksmall molecule
DB13144 LenograstimDrugbankbiotech
DB13200 LipegfilgrastimDrugbankbiotech