Entity Details

Primary name LYST_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99698
EntryNameLYST_HUMAN
FullNameLysosomal-trafficking regulator
TaxID9606
Evidenceevidence at protein level
Length3801
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesLYST

GO terms

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GOName
GO:0005829 cytosol
GO:0006909 phagocytosis
GO:0007040 lysosome organization
GO:0008104 protein localization
GO:0015031 protein transport
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0019901 protein kinase binding
GO:0030595 leukocyte chemotaxis
GO:0032438 melanosome organization
GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway
GO:0033364 mast cell secretory granule organization
GO:0042267 natural killer cell mediated cytotoxicity
GO:0042742 defense response to bacterium
GO:0042832 defense response to protozoan
GO:0043473 pigmentation
GO:0051607 defense response to virus

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000409 BEACH domainDomainDomain
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR023362 PH-BEACH domainDomainDomain
IPR030464 Lysosomal-trafficking regulatorFamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily
IPR036372 BEACH domain superfamilyFamilyHomologous superfamily

Diseases

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