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Entity Details
Primary name
SGMR1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q99720
EntryName
SGMR1_HUMAN
FullName
Sigma non-opioid intracellular receptor 1
TaxID
9606
Evidence
evidence at protein level
Length
223
SequenceStatus
complete
DateCreated
2006-12-12
DateModified
2021-06-02
Ontological Relatives
Genes
SIGMAR1
GO terms
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GO
Name
GO:0004985
G protein-coupled opioid receptor activity
GO:0005635
nuclear envelope
GO:0005637
nuclear inner membrane
GO:0005640
nuclear outer membrane
GO:0005783
endoplasmic reticulum
GO:0005789
endoplasmic reticulum membrane
GO:0005811
lipid droplet
GO:0005829
cytosol
GO:0006869
lipid transport
GO:0007399
nervous system development
GO:0014069
postsynaptic density
GO:0016020
membrane
GO:0016021
integral component of membrane
GO:0030426
growth cone
GO:0031410
cytoplasmic vesicle
GO:0036474
cell death in response to hydrogen peroxide
GO:0042802
identical protein binding
GO:0043523
regulation of neuron apoptotic process
GO:0070207
protein homotrimerization
GO:0098839
postsynaptic density membrane
Subcellular Location
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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasmic vesicle
Endoplasmic reticulum membrane
Lipid droplet
Membrane
Nucleus envelope
Nucleus inner membrane
Nucleus outer membrane
Domains
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Domain
Name
Category
Type
IPR006716
ERG2/sigma1 receptor-like
Family
Family
Diseases
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Drugs
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Drug
Name
Source
Type
DB00321
Amitriptyline
Drugbank
small molecule
DB00409
Remoxipride
Drugbank
small molecule
DB00502
Haloperidol
Drugbank
small molecule
DB00514
Dextromethorphan
Drugbank
small molecule
DB00540
Nortriptyline
Drugbank
small molecule
DB00574
Fenfluramine
Drugbank
small molecule
DB00652
Pentazocine
Drugbank
small molecule
DB00907
Cocaine
Drugbank
small molecule
DB00956
Hydrocodone
Drugbank
small molecule
DB01104
Sertraline
Drugbank
small molecule
DB01488
Dimethyltryptamine
Drugbank
small molecule
DB01708
Prasterone
Drugbank
small molecule
DB03575
Phencyclidine
Drugbank
small molecule
DB06174
Noscapine
Drugbank
small molecule
DB09014
Captodiame
Drugbank
small molecule
DB11186
Pentoxyverine
Drugbank
small molecule
Interactions
14 interactions
Interactor
Partner
Sources
Publications
Link
SGMR1_HUMAN
PDZ11_HUMAN
BioGRID, IntAct
21988832
details
SGMR1_HUMAN
SGMR1_HUMAN
DIP, IntAct
23637801
27042935
30291362
details
SGMR1_HUMAN
DRD2_HUMAN
IntAct
23637801
details
SGMR1_HUMAN
GHSR_HUMAN
BioGRID, IntAct
29876881
details
SGMR1_HUMAN
APBB1_HUMAN
IntAct
32814053
details
SGMR1_HUMAN
SERPH_HUMAN
IntAct
32814053
details
SGMR1_HUMAN
KAPCA_HUMAN
IntAct
32814053
details
SGMR1_HUMAN
TGFR2_HUMAN
IntAct
32814053
details
SGMR1_HUMAN
CAC1B_HUMAN
BioGRID
28603497
details
SGMR1_HUMAN
STOM_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
SGMR1_HUMAN
ITPR3_HUMAN
BioGRID, HPRD
11149946
details
SGMR1_HUMAN
ANK2_HUMAN
BioGRID, HPRD
11149946
details
SGMR1_HUMAN
KCNH2_HUMAN
BioGRID
21680736
details
SGMR1_HUMAN
OPRM_HUMAN
BioGRID
20089882
details
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