Entity Details

Primary name SELS_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BQE4
EntryNameSELS_HUMAN
FullNameSelenoprotein S
TaxID9606
Evidenceevidence at protein level
Length189
SequenceStatuscomplete
DateCreated2003-08-04
DateModified2021-06-02

Ontological Relatives

GenesSELENOS

GO terms

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GOName
GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005881 cytoplasmic microtubule
GO:0005886 plasma membrane
GO:0006111 regulation of gluconeogenesis
GO:0006983 ER overload response
GO:0009749 response to glucose
GO:0016209 antioxidant activity
GO:0016567 protein ubiquitination
GO:0019899 enzyme binding
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030433 ubiquitin-dependent ERAD pathway
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0030970 retrograde protein transport, ER to cytosol
GO:0032715 negative regulation of interleukin-6 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032869 cellular response to insulin stimulus
GO:0034361 very-low-density lipoprotein particle
GO:0034362 low-density lipoprotein particle
GO:0034599 cellular response to oxidative stress
GO:0036502 Derlin-1-VIMP complex
GO:0036513 Derlin-1 retrotranslocation complex
GO:0038023 signaling receptor activity
GO:0045184 establishment of protein localization
GO:0045454 cell redox homeostasis
GO:0045719 negative regulation of glycogen biosynthetic process
GO:0046325 negative regulation of glucose import
GO:0050728 negative regulation of inflammatory response
GO:0051117 ATPase binding
GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process
GO:0051775 response to redox state
GO:0071222 cellular response to lipopolysaccharide
GO:0080164 regulation of nitric oxide metabolic process
GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1990381 ubiquitin-specific protease binding
GO:2000110 negative regulation of macrophage apoptotic process

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR009703 Selenoprotein SFamilyFamily

Diseases

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Interactions

27 interactions

InteractorPartnerSourcesPublicationsLink
SELS_HUMANDERL1_HUMANBioGRID, HPRD, IntAct15215856 16186509 16186510 16289116 17872946 21832065 22119785 34079125 details
SELS_HUMANSRPK2_HUMANBioGRID, IntAct23602568 details
SELS_HUMANAPOA5_HUMANBioGRID, IntAct32296183 details
SELS_HUMANKLDC2_HUMANBioGRID, IntAct22119785 28514442 30526872 details
SELS_HUMANMFHA1_HUMANBioGRID, IntAct29513927 details
SELS_HUMANTERA_HUMANBioGRID, HPRD, IntAct15215856 16289116 17872946 18199748 21832065 22119785 24424410 24700463 25008318 26504085 26549226 29540532 29599191 details
SELS_HUMANSAA1_HUMANBioGRID, HPRD12031974 details
SELS_HUMANIMB1_HUMANBioGRID21832065 details
SELS_HUMANGT2D1_HUMANBioGRID26275350 details
SELS_HUMANCFTR_HUMANBioGRID29555962 details
SELS_HUMANPPARG_HUMANBioGRID30082770 details
SELS_HUMANDERL2_HUMANBioGRID, IntAct16186509 22119785 23867461 details
SELS_HUMANSELK_HUMANBioGRID, IntAct22119785 26504085 details
SELS_HUMANUFD1_HUMANBioGRID15215856 details
SELS_HUMANHSP74_HUMANBioGRID15215856 details
SELS_HUMANSVIP_HUMANBioGRID17872946 details
SELS_HUMANSYVN1_HUMANBioGRID16289116 17872946 details
SELS_HUMANAMFR_HUMANBioGRID17872946 21832065 details
SELS_HUMANNPL4_HUMANBioGRID17872946 details
SELS_HUMANHERP1_HUMANBioGRID16289116 details
SELS_HUMANCAV1_HUMANBioGRID24089527 details
SELS_HUMANPGH2_HUMANBioGRID24089527 details
SELS_HUMANTM129_HUMANBioGRID24807418 details
SELS_HUMANCKAP4_HUMANBioGRID25008318 34079125 details
SELS_HUMANSNTG2_HUMANBioGRID25008318 details
SELS_HUMANRNF5_HUMANBioGRID29555962 details
SELS_HUMANST7_HUMANBioGRID29395067 details