Entity Details

Primary name SOX12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15370
EntryNameSOX12_HUMAN
FullNameTranscription factor SOX-12
TaxID9606
Evidenceevidence at transcript level
Length315
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesSOX12

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005654 nucleoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0009653 anatomical structure morphogenesis
GO:0021510 spinal cord development
GO:0030154 cell differentiation
GO:0032993 protein-DNA complex
GO:0045165 cell fate commitment
GO:0045591 positive regulation of regulatory T cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR017386 Transcription factor SOX-12/11/4FamilyFamily
IPR031267 Transcription factor SOX-12FamilyFamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
SOX12_HUMANSMAD4_HUMANBioGRID, IntAct21988832 details
SOX12_HUMANDPOD2_HUMANBioGRID, IntAct21988832 details
SOX12_HUMANSPEE_HUMANBioGRID, IntAct21988832 details