Entity Details

Primary name CLD3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15551
EntryNameCLD3_HUMAN
FullNameClaudin-3
TaxID9606
Evidenceevidence at protein level
Length220
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesCLDN3

GO terms

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GOName
GO:0001666 response to hypoxia
GO:0001934 positive regulation of protein phosphorylation
GO:0003382 epithelial cell morphogenesis
GO:0004888 transmembrane signaling receptor activity
GO:0005198 structural molecule activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0005923 bicellular tight junction
GO:0007155 cell adhesion
GO:0008285 negative regulation of cell population proliferation
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0014045 establishment of endothelial blood-brain barrier
GO:0016021 integral component of membrane
GO:0016327 apicolateral plasma membrane
GO:0016328 lateral plasma membrane
GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0022604 regulation of cell morphogenesis
GO:0030335 positive regulation of cell migration
GO:0030336 negative regulation of cell migration
GO:0031532 actin cytoskeleton reorganization
GO:0032991 protein-containing complex
GO:0034331 cell junction maintenance
GO:0035633 maintenance of blood-brain barrier
GO:0042802 identical protein binding
GO:0043296 apical junction complex
GO:0045471 response to ethanol
GO:0061045 negative regulation of wound healing
GO:0070160 tight junction
GO:0070830 bicellular tight junction assembly
GO:0090303 positive regulation of wound healing
GO:0090559 regulation of membrane permeability
GO:0150111 regulation of transepithelial transport
GO:1901890 positive regulation of cell junction assembly
GO:1903348 positive regulation of bicellular tight junction assembly
GO:1905050 positive regulation of metallopeptidase activity

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR003549 Claudin-3FamilyFamily
IPR004031 PMP-22/EMP/MP20/Claudin superfamilyFamilyFamily
IPR006187 ClaudinFamilyFamily
IPR017974 Claudin, conserved siteSiteConserved site

Diseases

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