Entity Details

Primary name ARHG4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NR80
EntryNameARHG4_HUMAN
FullNameRho guanine nucleotide exchange factor 4
TaxID9606
Evidenceevidence at protein level
Length690
SequenceStatuscomplete
DateCreated2004-09-27
DateModified2021-06-02

Ontological Relatives

GenesARHGEF4

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005829 cytosol
GO:0007186 G protein-coupled receptor signaling pathway
GO:0019904 protein domain specific binding
GO:0030032 lamellipodium assembly
GO:0032587 ruffle membrane
GO:0035556 intracellular signal transduction
GO:0043065 positive regulation of apoptotic process
GO:0046847 filopodium assembly
GO:0051056 regulation of small GTPase mediated signal transduction

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001452 SH3 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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