Entity Details

Primary name RHG35_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NRY4
EntryNameRHG35_HUMAN
FullNameRho GTPase-activating protein 35
TaxID9606
Evidenceevidence at protein level
Length1499
SequenceStatuscomplete
DateCreated2003-04-04
DateModified2021-06-02

Ontological Relatives

GenesARHGAP35

GO terms

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GOName
GO:0001843 neural tube closure
GO:0003677 DNA binding
GO:0003924 GTPase activity
GO:0005096 GTPase activator activity
GO:0005525 GTP binding
GO:0005543 phospholipid binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0008064 regulation of actin polymerization or depolymerization
GO:0008360 regulation of cell shape
GO:0010976 positive regulation of neuron projection development
GO:0015629 actin cytoskeleton
GO:0016477 cell migration
GO:0021955 central nervous system neuron axonogenesis
GO:0030879 mammary gland development
GO:0030900 forebrain development
GO:0030950 establishment or maintenance of actin cytoskeleton polarity
GO:0031668 cellular response to extracellular stimulus
GO:0032956 regulation of actin cytoskeleton organization
GO:0035024 negative regulation of Rho protein signal transduction
GO:0036064 ciliary basal body
GO:0043010 camera-type eye development
GO:0043116 negative regulation of vascular permeability
GO:0044319 wound healing, spreading of cells
GO:0045724 positive regulation of cilium assembly
GO:0050770 regulation of axonogenesis
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0097485 neuron projection guidance

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR001806 Small GTPaseFamilyFamily
IPR002713 FF domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR032835 Rho GTPase-activating protein, FF domainDomainDomain
IPR036517 FF domain superfamilyFamilyHomologous superfamily
IPR039006 Rho GTPase-activating protein, pG2 domainDomainDomain
IPR039007 Rho GTPase-activating protein, pG1 domainDomainDomain

Diseases

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