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Entity Details
Primary name
SENP1_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9P0U3
EntryName
SENP1_HUMAN
FullName
Sentrin-specific protease 1
TaxID
9606
Evidence
evidence at protein level
Length
644
SequenceStatus
complete
DateCreated
2002-11-28
DateModified
2021-06-02
Ontological Relatives
Genes
SENP1
GO terms
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GO
Name
GO:0004175
endopeptidase activity
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005737
cytoplasm
GO:0005925
focal adhesion
GO:0006508
proteolysis
GO:0006919
activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0016926
protein desumoylation
GO:0031965
nuclear membrane
GO:0045944
positive regulation of transcription by RNA polymerase II
GO:0070140
SUMO-specific isopeptidase activity
GO:0097190
apoptotic signaling pathway
Subcellular Location
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Subcellular Location
Cytoplasm
Nucleus
Domains
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Domain
Name
Category
Type
IPR003653
Ulp1 protease family, C-terminal catalytic domain
Domain
Domain
IPR038765
Papain-like cysteine peptidase superfamily
Family
Homologous superfamily
Diseases
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Drugs
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Interactions
36 interactions
Interactor
Partner
Sources
Publications
Link
SENP1_HUMAN
SUMO1_HUMAN
BioGRID, DIP, IntAct, MINT
15896780
16553580
16608850
17000875
17099698
22878415
30082317
32296183
details
SENP1_HUMAN
SUMO3_HUMAN
BioGRID, MINT
16553580
16608850
22878415
details
SENP1_HUMAN
SUMO2_HUMAN
BioGRID, DIP, IntAct
16553580
17000875
17099698
22878415
32296183
details
SENP1_HUMAN
RAGP1_HUMAN
BioGRID, DIP
16553580
17099698
25027693
27449295
details
SENP1_HUMAN
SENP1_HUMAN
BioGRID
17704192
details
SENP1_HUMAN
PARP1_HUMAN
BioGRID
19622798
details
SENP1_HUMAN
GCM1_HUMAN
BioGRID
21791615
details
SENP1_HUMAN
RBP2_HUMAN
BioGRID
22194619
details
SENP1_HUMAN
HIPK2_HUMAN
BioGRID
16253240
details
SENP1_HUMAN
A4_HUMAN
BioGRID
21244100
21832049
details
SENP1_HUMAN
UBP25_HUMAN
BioGRID
18538659
details
SENP1_HUMAN
RBGP1_HUMAN
BioGRID
16608850
details
SENP1_HUMAN
SP100_HUMAN
BioGRID
22878415
details
SENP1_HUMAN
CAV3_HUMAN
BioGRID
21362625
details
SENP1_HUMAN
UBE2K_HUMAN
BioGRID
21098080
details
SENP1_HUMAN
PML_HUMAN
BioGRID
21098080
details
SENP1_HUMAN
ZN420_HUMAN
BioGRID
25691462
details
SENP1_HUMAN
NACC1_HUMAN
BioGRID
25891951
details
SENP1_HUMAN
PIM1_HUMAN
BioGRID
28620180
details
SENP1_HUMAN
CHD3_HUMAN
BioGRID
30082317
details
SENP1_HUMAN
PIAS3_HUMAN
BioGRID
30082317
details
SENP1_HUMAN
RL11_HUMAN
BioGRID
30024791
details
SENP1_HUMAN
UBP28_HUMAN
BioGRID
30622440
details
SENP1_HUMAN
HIPK1_HUMAN
BioGRID
18219322
details
SENP1_HUMAN
HDAC4_HUMAN
BioGRID
20079608
31040226
details
SENP1_HUMAN
RUVB2_HUMAN
BioGRID
16699503
20603076
details
SENP1_HUMAN
HDAC1_HUMAN
BioGRID
15199155
details
SENP1_HUMAN
HDAC2_HUMAN
BioGRID
22493095
details
SENP1_HUMAN
PRDM1_HUMAN
BioGRID
21722636
details
SENP1_HUMAN
P53_HUMAN
BioGRID
19339993
details
SENP1_HUMAN
ARRB2_HUMAN
BioGRID
25425640
details
SENP1_HUMAN
SNAI2_HUMAN
BioGRID
30612578
details
SENP1_HUMAN
OTUB2_HUMAN
BioGRID
30472188
details
SENP1_HUMAN
ST7_HUMAN
BioGRID
29395067
details
SENP1_HUMAN
LZTS2_HUMAN
BioGRID
29395067
details
SENP1_HUMAN
THIO_HUMAN
BioGRID
18219322
details
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