Entity Details

Primary name MALT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UDY8
EntryNameMALT1_HUMAN
FullNameMucosa-associated lymphoid tissue lymphoma translocation protein 1
TaxID9606
Evidenceevidence at protein level
Length824
SequenceStatuscomplete
DateCreated2002-05-02
DateModified2021-06-02

Ontological Relatives

GenesMALT1

GO terms

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GOName
GO:0001650 fibrillar center
GO:0001923 B-1 B cell differentiation
GO:0002020 protease binding
GO:0002096 polkadots
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002726 positive regulation of T cell cytokine production
GO:0004175 endopeptidase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006508 proteolysis
GO:0006952 defense response
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0008233 peptidase activity
GO:0009620 response to fungus
GO:0031398 positive regulation of protein ubiquitination
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032449 CBM complex
GO:0032731 positive regulation of interleukin-1 beta production
GO:0032743 positive regulation of interleukin-2 production
GO:0032991 protein-containing complex
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042098 T cell proliferation
GO:0042113 B cell activation
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043621 protein self-association
GO:0045087 innate immune response
GO:0048471 perinuclear region of cytoplasm
GO:0050852 T cell receptor signaling pathway
GO:0050856 regulation of T cell receptor signaling pathway
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0051168 nuclear export
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:2000321 positive regulation of T-helper 17 cell differentiation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001309 Peptidase C14, p20 domainDomainDomain
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR029030 Caspase-like domain superfamilyFamilyHomologous superfamily
IPR033540 Mucosa-associated lymphoid tissue lymphoma translocation protein 1FamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR037940 MALT1, death domainDomainDomain
IPR041077 MALT1 immunoglobulin-like domainDomainDomain

Diseases

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Interactions

54 interactions

InteractorPartnerSourcesPublicationsLink
MALT1_HUMANBCL10_HUMANBioGRID, DIP, HPRD, InnateDB, IntAct, MINT11090634 11262391 14695475 17189706 17948050 18806265 19118383 19279678 19444310 20551178 21157432 21513986 22267217 22528498 22658522 23690623 24130731 25548215 25569716 25748427 27070702 27071417 27113748 27777308 29953499 30279415 31961340 33329596 details
MALT1_HUMANUBC_HUMANBioGRID, MINT17948050 31980531 details
MALT1_HUMANNEMO_HUMANBioGRID, IntAct, MINT17948050 18931663 19494296 25748427 27070702 details
MALT1_HUMANTRAF6_HUMANBioGRID, HPRD, IntAct, MINT15125833 17948050 19234489 22528498 23264041 25569716 29953499 details
MALT1_HUMANSUV91_HUMANBioGRID, MINT23455924 details
MALT1_HUMANKDM1A_HUMANBioGRID, MINT23455924 details
MALT1_HUMANCARM1_HUMANBioGRID, MINT23455924 details
MALT1_HUMANANM6_HUMANBioGRID, MINT23455924 details
MALT1_HUMANFEM1C_HUMANBioGRID, IntAct32296183 details
MALT1_HUMANFEM1A_HUMANBioGRID, IntAct32296183 details
MALT1_HUMANMALT1_HUMANBioGRID, DIP, HPRD11262391 14695475 19917778 21966355 22158899 22366302 29953499 31961340 details
MALT1_HUMANDYN2_HUMANIntAct32814053 details
MALT1_HUMANGRN_HUMANIntAct32814053 details
MALT1_HUMANHSPB1_HUMANIntAct32814053 details
MALT1_HUMANPAHX_HUMANIntAct32814053 details
MALT1_HUMANPRPS1_HUMANIntAct32814053 details
MALT1_HUMANWFS1_HUMANIntAct32814053 details
MALT1_HUMANBAG6_HUMANIntAct32814053 details
MALT1_HUMANKLF11_HUMANIntAct32814053 details
MALT1_HUMANKIF1B_HUMANIntAct32814053 details
MALT1_HUMANSPRE1_HUMANIntAct32814053 details
MALT1_HUMANATX3_HUMANBioGRID, IntAct29111377 32814053 details
MALT1_HUMANTRAF2_HUMANBioGRID, HPRD15125833 19234489 details
MALT1_HUMANRELB_HUMANBioGRID21873235 31961340 details
MALT1_HUMANUBP2_HUMANBioGRID23264041 28052131 details
MALT1_HUMANHECD3_HUMANBioGRID23358872 details
MALT1_HUMANUB2V2_HUMANBioGRID14695475 details
MALT1_HUMANUBE2N_HUMANBioGRID14695475 details
MALT1_HUMANHOIL1_HUMANBioGRID26525107 33329596 details
MALT1_HUMANSQSTM_HUMANBioGRID, HPRD, MINT16874300 details
MALT1_HUMANVHL_HUMANIntAct17353931 details
MALT1_HUMANKPCT_HUMANBioGRID, MINT17363905 details
MALT1_HUMANTAB2_HUMANBioGRID, MINT17948050 25748427 details
MALT1_HUMANM3K7_HUMANBioGRID, MINT17948050 25748427 details
MALT1_HUMANCAR11_HUMANBioGRID, IntAct, MINT17948050 22528498 23322406 25748427 31961340 33329596 details
MALT1_HUMANCSN5_HUMANBioGRID, MINT19444310 details
MALT1_HUMANCSN1_HUMANBioGRID, MINT19444310 details
MALT1_HUMANCASP8_HUMANInnateDB22267217 details
MALT1_HUMANSHRPN_HUMANBioGRID, IntAct27070702 33329596 details
MALT1_HUMANKPCD_HUMANBioGRID, IntAct22528498 details
MALT1_HUMANKC1A_HUMANBioGRID, DIP19118383 20551178 25088585 details
MALT1_HUMANTRAF3_HUMANIntAct19917778 details
MALT1_HUMANIKBA_HUMANBioGRID20551178 details
MALT1_HUMANKCC2G_HUMANBioGRID21513986 details
MALT1_HUMANDBLOH_HUMANBioGRID19234489 details
MALT1_HUMANDAB2_HUMANBioGRID22323290 details
MALT1_HUMANUSP9X_HUMANBioGRID23690623 details
MALT1_HUMANCHIP_HUMANBioGRID23322406 details
MALT1_HUMANRNF31_HUMANBioGRID24491438 33329596 details
MALT1_HUMANTNAP3_HUMANBioGRID24491438 details
MALT1_HUMANCAR14_HUMANBioGRID27071417 27113748 details
MALT1_HUMANARBK1_HUMANBioGRID31961340 details
MALT1_HUMANCYLD_HUMANBioGRID33329596 details
MALT1_HUMANOTUL_HUMANBioGRID33329596 details