Entity Details

Primary name PSME2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UL46
EntryNamePSME2_HUMAN
FullNameProteasome activator complex subunit 2
TaxID9606
Evidenceevidence at protein level
Length239
SequenceStatuscomplete
DateCreated2001-08-29
DateModified2021-06-02

Ontological Relatives

GenesPSME2

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000209 protein polyubiquitination
GO:0000502 proteasome complex
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006521 regulation of cellular amino acid metabolic process
GO:0008537 proteasome activator complex
GO:0010950 positive regulation of endopeptidase activity
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0016020 membrane
GO:0016579 protein deubiquitination
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0035722 interleukin-12-mediated signaling pathway
GO:0036388 pre-replicative complex assembly
GO:0038061 NIK/NF-kappaB signaling
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0042802 identical protein binding
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043488 regulation of mRNA stability
GO:0043687 post-translational protein modification
GO:0050852 T cell receptor signaling pathway
GO:0055085 transmembrane transport
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061133 endopeptidase activator activity
GO:0061136 regulation of proteasomal protein catabolic process
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070062 extracellular exosome
GO:0070498 interleukin-1-mediated signaling pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:2000045 regulation of G1/S transition of mitotic cell cycle

Subcellular Location

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Domains

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DomainNameCategoryType
IPR003185 Proteasome activator PA28, N-terminal domainDomainDomain
IPR003186 Proteasome activator PA28, C-terminal domainDomainDomain
IPR009077 Proteasome activator PA28FamilyFamily
IPR036252 Proteasome activator superfamilyFamilyHomologous superfamily
IPR036996 Proteasome activator PA28, N-terminal domain superfamilyFamilyHomologous superfamily
IPR036997 Proteasome activator PA28, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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