Entity Details

Primary name TLX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43763
EntryNameTLX2_HUMAN
FullNameT-cell leukemia homeobox protein 2
TaxID9606
Evidenceevidence at protein level
Length284
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesTLX2

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001707 mesoderm formation
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0043565 sequence-specific DNA binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048484 enteric nervous system development
GO:0048513 animal organ development
GO:0050774 negative regulation of dendrite morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain
IPR042247 T-cell leukemia homeobox protein 1/2/3FamilyFamily

Diseases

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