Entity Details

Primary name AFG32_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y4W6
EntryNameAFG32_HUMAN
FullNameAFG3-like protein 2
TaxID9606
Evidenceevidence at protein level
Length797
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesAFG3L2

GO terms

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GOName
GO:0004176 ATP-dependent peptidase activity
GO:0004222 metalloendopeptidase activity
GO:0005524 ATP binding
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005745 m-AAA complex
GO:0006508 proteolysis
GO:0006851 mitochondrial calcium ion transmembrane transport
GO:0007409 axonogenesis
GO:0007528 neuromuscular junction development
GO:0008053 mitochondrial fusion
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0016485 protein processing
GO:0016540 protein autoprocessing
GO:0021675 nerve development
GO:0033619 membrane protein proteolysis
GO:0034982 mitochondrial protein processing
GO:0036444 calcium import into the mitochondrion
GO:0040014 regulation of multicellular organism growth
GO:0042407 cristae formation
GO:0042552 myelination
GO:0051082 unfolded protein binding
GO:0051560 mitochondrial calcium ion homeostasis
GO:0060013 righting reflex
GO:0065003 protein-containing complex assembly

Subcellular Location

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Subcellular Location
Mitochondrion
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR000642 Peptidase M41DomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR003959 ATPase, AAA-type, coreDomainDomain
IPR003960 ATPase, AAA-type, conserved siteSiteConserved site
IPR005936 Peptidase, FtsHFamilyFamily
IPR011546 Peptidase M41, FtsH extracellularDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR037219 Peptidase M41-likeFamilyHomologous superfamily
IPR041569 AAA ATPase, AAA+ lid domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00171 ATPDrugbanksmall molecule