Entity Details

Primary name CP46A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y6A2
EntryNameCP46A_HUMAN
FullNameCholesterol 24-hydroxylase
TaxID9606
Evidenceevidence at protein level
Length500
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesCYP46A1

GO terms

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GOName
GO:0005506 iron ion binding
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006699 bile acid biosynthetic process
GO:0006707 cholesterol catabolic process
GO:0006805 xenobiotic metabolic process
GO:0007399 nervous system development
GO:0008395 steroid hydroxylase activity
GO:0016021 integral component of membrane
GO:0016125 sterol metabolic process
GO:0020037 heme binding
GO:0030425 dendrite
GO:0033781 cholesterol 24-hydroxylase activity
GO:0042448 progesterone metabolic process
GO:0062184 testosterone 16-beta-hydroxylase activity
GO:0098793 presynapse
GO:0098794 postsynapse
GO:1900271 regulation of long-term synaptic potentiation
GO:1903044 protein localization to membrane raft

Subcellular Location

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Subcellular Location
Cell junction
Cell projection
Endoplasmic reticulum membrane
Microsome membrane

Domains

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DomainNameCategoryType
IPR001128 Cytochrome P450FamilyFamily
IPR002401 Cytochrome P450, E-class, group IFamilyFamily
IPR017972 Cytochrome P450, conserved siteSiteConserved site
IPR036396 Cytochrome P450 superfamilyFamilyHomologous superfamily
IPR039983 Cholesterol 24-hydroxylaseFamilyFamily

Diseases

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Interactions

4 interactions