Entity Details

Primary name ATS4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO75173
EntryNameATS4_HUMAN
FullNameA disintegrin and metalloproteinase with thrombospondin motifs 4
TaxID9606
Evidenceevidence at protein level
Length837
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesADAMTS4

GO terms

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GOName
GO:0001501 skeletal system development
GO:0002020 protease binding
GO:0004222 metalloendopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006508 proteolysis
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0016607 nuclear speck
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
GO:0031012 extracellular matrix
GO:0046872 metal ion binding
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001590 Peptidase M12B, ADAM/reprolysinDomainDomain
IPR002870 Peptidase M12B, propeptideDomainDomain
IPR006586 ADAM, cysteine-rich domainDomainDomain
IPR010294 ADAM-TS Spacer 1DomainDomain
IPR013273 ADAMTS/ADAMTS-likeFamilyFamily
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR041645 ADAM cysteine-rich domain 2DomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB06822 TinzaparinDrugbanksmall molecule