Entity Details

Primary name KCNH1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95259
EntryNameKCNH1_HUMAN
FullNamePotassium voltage-gated channel subfamily H member 1
TaxID9606
Evidenceevidence at protein level
Length989
SequenceStatuscomplete
DateCreated2002-11-28
DateModified2021-06-02

Ontological Relatives

GenesKCNH1

GO terms

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GOName
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005516 calmodulin binding
GO:0005637 nuclear inner membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006813 potassium ion transport
GO:0007520 myoblast fusion
GO:0008076 voltage-gated potassium channel complex
GO:0030424 axon
GO:0030425 dendrite
GO:0031901 early endosome membrane
GO:0034765 regulation of ion transmembrane transport
GO:0042127 regulation of cell population proliferation
GO:0042391 regulation of membrane potential
GO:0042734 presynaptic membrane
GO:0043204 perikaryon
GO:0043231 intracellular membrane-bounded organelle
GO:0048015 phosphatidylinositol-mediated signaling
GO:0071277 cellular response to calcium ion
GO:0071805 potassium ion transmembrane transport
GO:0098839 postsynaptic density membrane
GO:1902936 phosphatidylinositol bisphosphate binding

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Early endosome membrane
Nucleus inner membrane
Perikaryon

Domains

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DomainNameCategoryType
IPR000014 PAS domainDomainDomain
IPR000595 Cyclic nucleotide-binding domainDomainDomain
IPR000700 PAS-associated, C-terminalDomainDomain
IPR001610 PAC motifRepeatRepeat
IPR003938 Potassium channel, voltage-dependent, EAG/ELK/ERGFamilyFamily
IPR003949 Potassium channel, voltage-dependent, EAGFamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR014710 RmlC-like jelly roll foldFamilyHomologous superfamily
IPR018490 Cyclic nucleotide-binding-likeFamilyHomologous superfamily
IPR030170 Potassium voltage-gated channel subfamily H member 1FamilyFamily
IPR035965 PAS domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00228 EnfluraneDrugbanksmall molecule
DB00458 ImipramineDrugbanksmall molecule
DB00637 AstemizoleDrugbanksmall molecule
DB01069 PromethazineDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule