Entity Details

Primary name CRTAM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95727
EntryNameCRTAM_HUMAN
FullNameCytotoxic and regulatory T-cell molecule
TaxID9606
Evidenceevidence at protein level
Length393
SequenceStatuscomplete
DateCreated2007-06-26
DateModified2021-06-02

Ontological Relatives

GenesCRTAM

GO terms

Show/Hide Table
GOName
GO:0001768 establishment of T cell polarity
GO:0001772 immunological synapse
GO:0001819 positive regulation of cytokine production
GO:0002250 adaptive immune response
GO:0002355 detection of tumor cell
GO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0005102 signaling receptor binding
GO:0005886 plasma membrane
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0008037 cell recognition
GO:0016021 integral component of membrane
GO:0032729 positive regulation of interferon-gamma production
GO:0042802 identical protein binding
GO:0045580 regulation of T cell differentiation
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0046007 negative regulation of activated T cell proliferation
GO:0050776 regulation of immune response
GO:0050863 regulation of T cell activation
GO:0051606 detection of stimulus
GO:0097021 lymphocyte migration into lymphoid organs
GO:2001185 regulation of CD8-positive, alpha-beta T cell activation

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013162 CD80-like, immunoglobulin C2-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

2 interactions