Entity Details

Primary name CLD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95832
EntryNameCLD1_HUMAN
FullNameClaudin-1
TaxID9606
Evidenceevidence at protein level
Length211
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesCLDN1

GO terms

Show/Hide Table
GOName
GO:0001618 virus receptor activity
GO:0005198 structural molecule activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005923 bicellular tight junction
GO:0007155 cell adhesion
GO:0007568 aging
GO:0008065 establishment of blood-nerve barrier
GO:0009636 response to toxic substance
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016328 lateral plasma membrane
GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0030335 positive regulation of cell migration
GO:0032496 response to lipopolysaccharide
GO:0032991 protein-containing complex
GO:0034331 cell junction maintenance
GO:0035633 maintenance of blood-brain barrier
GO:0042538 hyperosmotic salinity response
GO:0042802 identical protein binding
GO:0045216 cell-cell junction organization
GO:0045471 response to ethanol
GO:0051259 protein complex oligomerization
GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing
GO:0061436 establishment of skin barrier
GO:0061772 xenobiotic transport across blood-nerve barrier
GO:0070160 tight junction
GO:0070673 response to interleukin-18
GO:0070830 bicellular tight junction assembly
GO:0071284 cellular response to lead ion
GO:0071346 cellular response to interferon-gamma
GO:0071356 cellular response to tumor necrosis factor
GO:0071548 response to dexamethasone
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:0090303 positive regulation of wound healing
GO:0090557 establishment of endothelial intestinal barrier
GO:0097421 liver regeneration
GO:1903348 positive regulation of bicellular tight junction assembly
GO:1903545 cellular response to butyrate

Subcellular Location

Show/Hide Table
Subcellular Location
Basolateral cell membrane
Cell junction
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR003548 Claudin-1FamilyFamily
IPR004031 PMP-22/EMP/MP20/Claudin superfamilyFamilyFamily
IPR006187 ClaudinFamilyFamily
IPR017974 Claudin, conserved siteSiteConserved site

Diseases

Show/Hide Table