Entity Details

Primary name TBX18_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95935
EntryNameTBX18_HUMAN
FullNameT-box transcription factor TBX18
TaxID9606
Evidenceevidence at protein level
Length607
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesTBX18

GO terms

Show/Hide Table
GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001708 cell fate specification
GO:0001756 somitogenesis
GO:0003163 sinoatrial node development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0016331 morphogenesis of embryonic epithelium
GO:0042803 protein homodimerization activity
GO:0051145 smooth muscle cell differentiation
GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0060930 sinoatrial node cell fate commitment
GO:0060931 sinoatrial node cell development
GO:0072189 ureter development
GO:0090103 cochlea morphogenesis
GO:0090571 RNA polymerase II transcription repressor complex
GO:0098907 regulation of SA node cell action potential
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001699 Transcription factor, T-boxFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR018186 Transcription factor, T-box, conserved siteSiteConserved site
IPR036960 T-box superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
TBX18_HUMANTRAF1_HUMANBioGRID, IntAct32296183 details
TBX18_HUMANPKHG4_HUMANBioGRID, IntAct32296183 details
TBX18_HUMANARC_HUMANBioGRID, IntAct32296183 details
TBX18_HUMANKRA81_HUMANBioGRID, IntAct32296183 details