Entity Details

Primary name EOMES_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95936
EntryNameEOMES_HUMAN
FullNameEomesodermin homolog
TaxID9606
Evidenceevidence at protein level
Length686
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesEOMES

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001706 endoderm formation
GO:0001707 mesoderm formation
GO:0001708 cell fate specification
GO:0001714 endodermal cell fate specification
GO:0001947 heart looping
GO:0002250 adaptive immune response
GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007420 brain development
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060706 cell differentiation involved in embryonic placenta development
GO:0060809 mesodermal to mesenchymal transition involved in gastrulation
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001699 Transcription factor, T-boxFamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR018186 Transcription factor, T-box, conserved siteSiteConserved site
IPR032385 T-box transcription factor-associatedDomainDomain
IPR036960 T-box superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
EOMES_HUMANPFD1_HUMANBioGRID, MINT21900206 details
EOMES_HUMANOTP_HUMANBioGRID, IntAct32296183 details