Entity Details

Primary name FETUA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02765
EntryNameFETUA_HUMAN
FullNameAlpha-2-HS-glycoprotein
TaxID9606
Evidenceevidence at protein level
Length367
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesAHSG

GO terms

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GOName
GO:0001501 skeletal system development
GO:0002576 platelet degranulation
GO:0004866 endopeptidase inhibitor activity
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005788 endoplasmic reticulum lumen
GO:0005794 Golgi apparatus
GO:0006907 pinocytosis
GO:0006953 acute-phase response
GO:0010951 negative regulation of endopeptidase activity
GO:0019210 kinase inhibitor activity
GO:0030500 regulation of bone mineralization
GO:0030502 negative regulation of bone mineralization
GO:0031012 extracellular matrix
GO:0031093 platelet alpha granule lumen
GO:0034774 secretory granule lumen
GO:0043312 neutrophil degranulation
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0046627 negative regulation of insulin receptor signaling pathway
GO:0050727 regulation of inflammatory response
GO:0050766 positive regulation of phagocytosis
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0072562 blood microparticle

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000010 Cystatin domainDomainDomain
IPR001363 Proteinase inhibitor I25C, fetuin, conserved siteSiteConserved site
IPR025760 Fetuin-A-type cystatin domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule