Entity Details

Primary name CXL10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP02778
EntryNameCXL10_HUMAN
FullNameC-X-C motif chemokine 10
TaxID9606
Evidenceevidence at protein level
Length98
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesCXCL10

GO terms

Show/Hide Table
GOName
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0007517 muscle organ development
GO:0008009 chemokine activity
GO:0008015 blood circulation
GO:0008201 heparin binding
GO:0008284 positive regulation of cell population proliferation
GO:0008603 cAMP-dependent protein kinase regulator activity
GO:0009409 response to cold
GO:0009897 external side of plasma membrane
GO:0010332 response to gamma radiation
GO:0010818 T cell chemotaxis
GO:0010819 regulation of T cell chemotaxis
GO:0010996 response to auditory stimulus
GO:0016525 negative regulation of angiogenesis
GO:0019221 cytokine-mediated signaling pathway
GO:0030593 neutrophil chemotaxis
GO:0031640 killing of cells of other organism
GO:0033280 response to vitamin D
GO:0034605 cellular response to heat
GO:0042056 chemoattractant activity
GO:0042118 endothelial cell activation
GO:0042127 regulation of cell population proliferation
GO:0042981 regulation of apoptotic process
GO:0045236 CXCR chemokine receptor binding
GO:0045662 negative regulation of myoblast differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048248 CXCR3 chemokine receptor binding
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070098 chemokine-mediated signaling pathway
GO:0071222 cellular response to lipopolysaccharide
GO:0090026 positive regulation of monocyte chemotaxis
GO:0098586 cellular response to virus
GO:0140374 antiviral innate immune response
GO:1901509 regulation of endothelial tube morphogenesis
GO:1901740 negative regulation of myoblast fusion
GO:2000406 positive regulation of T cell migration

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR001089 CXC chemokineFamilyFamily
IPR001811 Chemokine interleukin-8-like domainDomainDomain
IPR018048 CXC chemokine, conserved siteSiteConserved site
IPR033899 CXC Chemokine domainDomainDomain
IPR036048 Chemokine interleukin-8-like superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB04487 N-MethylleucineDrugbanksmall molecule
DB06116 EldelumabDrugbankbiotech
DB11338 Clove oilDrugbankbiotech