Entity Details

Primary name CD2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP06729
EntryNameCD2_HUMAN
FullNameT-cell surface antigen CD2
TaxID9606
Evidenceevidence at protein level
Length351
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesCD2

GO terms

Show/Hide Table
GOName
GO:0001766 membrane raft polarization
GO:0005102 signaling receptor binding
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0006915 apoptotic process
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0009898 cytoplasmic side of plasma membrane
GO:0009986 cell surface
GO:0030101 natural killer cell activation
GO:0030887 positive regulation of myeloid dendritic cell activation
GO:0030971 receptor tyrosine kinase binding
GO:0032729 positive regulation of interferon-gamma production
GO:0032757 positive regulation of interleukin-8 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0032991 protein-containing complex
GO:0034113 heterotypic cell-cell adhesion
GO:0038023 signaling receptor activity
GO:0042110 T cell activation
GO:0042802 identical protein binding
GO:0043621 protein self-association
GO:0045121 membrane raft
GO:0045580 regulation of T cell differentiation
GO:0046658 anchored component of plasma membrane
GO:0050900 leukocyte migration
GO:0098609 cell-cell adhesion

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR008424 Immunoglobulin C2-setDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR015632 T-cell surface antigen CD2FamilyFamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00092 AlefaceptDrugbankbiotech
DB06371 SiplizumabDrugbankbiotech