Entity Details

Primary name KLK3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07288
EntryNameKLK3_HUMAN
FullNameProstate-specific antigen
TaxID9606
Evidenceevidence at protein level
Length261
SequenceStatuscomplete
DateCreated1988-04-01
DateModified2021-06-02

Ontological Relatives

GenesKLK3

GO terms

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GOName
GO:0002803 positive regulation of antibacterial peptide production
GO:0003073 regulation of systemic arterial blood pressure
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0006508 proteolysis
GO:0008236 serine-type peptidase activity
GO:0016525 negative regulation of angiogenesis
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0030141 secretory granule
GO:0031638 zymogen activation
GO:0032991 protein-containing complex
GO:0044267 cellular protein metabolic process
GO:0060765 regulation of androgen receptor signaling pathway
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00834 MifepristoneDrugbanksmall molecule
DB04839 Cyproterone acetateDrugbanksmall molecule
DB16019 Gallium Ga-68 gozetotideDrugbanksmall molecule