Entity Details

Primary name FGF4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP08620
EntryNameFGF4_HUMAN
FullNameFibroblast growth factor 4
TaxID9606
Evidenceevidence at protein level
Length206
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesFGF4

GO terms

Show/Hide Table
GOName
GO:0000165 MAPK cascade
GO:0001502 cartilage condensation
GO:0001934 positive regulation of protein phosphorylation
GO:0005104 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0008201 heparin binding
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009887 animal organ morphogenesis
GO:0010463 mesenchymal cell proliferation
GO:0010628 positive regulation of gene expression
GO:0019827 stem cell population maintenance
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0035116 embryonic hindlimb morphogenesis
GO:0042475 odontogenesis of dentin-containing tooth
GO:0043066 negative regulation of apoptotic process
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:0060363 cranial suture morphogenesis
GO:0060561 apoptotic process involved in morphogenesis
GO:0060591 chondroblast differentiation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1990830 cellular response to leukemia inhibitory factor
GO:2000544 regulation of endothelial cell chemotaxis to fibroblast growth factor

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR002209 Fibroblast growth factor familyFamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR028239 Fibroblast growth factor 4FamilyFamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00686 Pentosan polysulfateDrugbanksmall molecule
DB01109 HeparinDrugbanksmall molecule
DB05309 TP-508Drugbanksmall molecule