Entity Details

Primary name MTAP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11137
EntryNameMTAP2_HUMAN
FullNameMicrotubule-associated protein 2
TaxID9606
Evidenceevidence at protein level
Length1827
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesMAP2

GO terms

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GOName
GO:0000226 microtubule cytoskeleton organization
GO:0001578 microtubule bundle formation
GO:0002162 dystroglycan binding
GO:0005198 structural molecule activity
GO:0005516 calmodulin binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005875 microtubule associated complex
GO:0008017 microtubule binding
GO:0016358 dendrite development
GO:0021954 central nervous system neuron development
GO:0030425 dendrite
GO:0030517 negative regulation of axon extension
GO:0031113 regulation of microtubule polymerization
GO:0031115 negative regulation of microtubule polymerization
GO:0031175 neuron projection development
GO:0032839 dendrite cytoplasm
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043194 axon initial segment
GO:0043198 dendritic shaft
GO:0043203 axon hillock
GO:0044294 dendritic growth cone
GO:0044307 dendritic branch
GO:0048156 tau protein binding
GO:0048813 dendrite morphogenesis
GO:0097441 basal dendrite
GO:0150001 primary dendrite
GO:0150002 distal dendrite
GO:0150014 apical distal dendrite
GO:1901953 positive regulation of anterograde dense core granule transport
GO:1902513 regulation of organelle transport along microtubule
GO:1902737 dendritic filopodium
GO:1903744 positive regulation of anterograde synaptic vesicle transport
GO:1903827 regulation of cellular protein localization
GO:1904527 negative regulation of microtubule binding
GO:1990635 proximal dendrite
GO:1990769 proximal neuron projection
GO:2000575 obsolete negative regulation of microtubule motor activity

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR001084 Microtubule associated protein, tubulin-binding repeatRepeatRepeat
IPR013588 MAP2/Tau projectionDomainDomain
IPR030797 Microtubule-associated protein 2FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01196 EstramustineDrugbanksmall molecule
DB01229 PaclitaxelDrugbanksmall molecule
DB01248 DocetaxelDrugbanksmall molecule