Entity Details

Primary name GTR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11168
EntryNameGTR2_HUMAN
FullNameSolute carrier family 2, facilitated glucose transporter member 2
TaxID9606
Evidenceevidence at protein level
Length524
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesSLC2A2

GO terms

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GOName
GO:0005353 fructose transmembrane transporter activity
GO:0005355 glucose transmembrane transporter activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005903 brush border
GO:0005911 cell-cell junction
GO:0005975 carbohydrate metabolic process
GO:0008645 hexose transmembrane transport
GO:0015755 fructose transmembrane transport
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0033300 dehydroascorbic acid transmembrane transporter activity
GO:0050796 regulation of insulin secretion
GO:0055056 D-glucose transmembrane transporter activity
GO:0070837 dehydroascorbic acid transport
GO:0106001 intestinal hexose absorption
GO:1904659 glucose transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR002440 Glucose transporter, type 2 (GLUT2)FamilyFamily
IPR003663 Sugar/inositol transporterFamilyFamily
IPR005828 Major facilitator, sugar transporter-likeFamilyFamily
IPR005829 Sugar transporter, conserved siteSiteConserved site
IPR020846 Major facilitator superfamily domainDomainDomain
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00428 StreptozocinDrugbanksmall molecule
DB01914 D-glucoseSwissprotsmall molecule
DB09341 Dextrose, unspecified formSwissprotsmall molecule
DB09344 Invert sugarSwissprotsmall molecule
DB09502 Fludeoxyglucose (18F)Swissprotsmall molecule