Entity Details

Primary name ADHX_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11766
EntryNameADHX_HUMAN
FullNameAlcohol dehydrogenase class-3
TaxID9606
Evidenceevidence at protein level
Length374
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesADH5

GO terms

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GOName
GO:0001523 retinoid metabolic process
GO:0003016 respiratory system process
GO:0004024 alcohol dehydrogenase activity, zinc-dependent
GO:0005504 fatty acid binding
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006069 ethanol oxidation
GO:0008270 zinc ion binding
GO:0009055 electron transfer activity
GO:0010430 fatty acid omega-oxidation
GO:0018119 peptidyl-cysteine S-nitrosylation
GO:0018467 formaldehyde dehydrogenase activity
GO:0032496 response to lipopolysaccharide
GO:0042802 identical protein binding
GO:0045777 positive regulation of blood pressure
GO:0046294 formaldehyde catabolic process
GO:0051409 response to nitrosative stress
GO:0051775 response to redox state
GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase activity
GO:0070062 extracellular exosome
GO:0106321 S-(hydroxymethyl)glutathione dehydrogenase NADP activity
GO:0106322 S-(hydroxymethyl)glutathione dehydrogenase NAD activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002328 Alcohol dehydrogenase, zinc-type, conserved siteSiteConserved site
IPR011032 GroES-like superfamilyFamilyHomologous superfamily
IPR013149 Alcohol dehydrogenase, C-terminalDomainDomain
IPR013154 Alcohol dehydrogenase, N-terminalDomainDomain
IPR014183 Alcohol dehydrogenase class IIIFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB01020 Isosorbide mononitrateDrugbanksmall molecule
DB03017 Lauric acidDrugbanksmall molecule
DB03704 12-Hydroxydodecanoic AcidDrugbanksmall molecule
DB04153 S-Hydroxymethyl GlutathioneDrugbanksmall molecule
DB11077 Polyethylene glycol 400Drugbanksmall molecule
DB12612 OzanimodDrugbanksmall molecule